Production of dengue 2 envelope domain III in plant using CPMV - based vector system
نویسندگان
چکیده
Background The envelope protein (E protein) of dengue virus is responsible for binding the virus to the host cell. This protein is considered an important immunogen for neutralization of the virus, the only able to induce the production of neutralizing antibodies [1]. The aim of this study was to use the Cowpea Mosaic Virus (CPMV) as a vector to express, on cowpea plants, Vigna unguiculata L. (Walp) the gene fragment that encodes for domain III of the E protein of dengue 2 virus.
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